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Relation between Blood Pressure and Pulse Wave Velocity for Human Arteries

Release time:November 29, 2019

Topic: Relation between Blood Pressure and Pulse Wave Velocity for Human Arteries

Speaker: Prof. Yonggang Huang

Time: Thursday, December 5, 2019, 10:00 am

Location: The grand lecture hall of Ruxin Conference Center

Abstract:

Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.

Biography:

Yonggang Huang, Honorary Professor of Beihang university, is a member of US National Academy of Engineering, a foreign member of Academia Europaea, and a foreign member of Chinese Academy of Sciences. He is committed to the interdisciplinary study of mechanics, materials and electronic information, whose research achievements have produced extensive and important academic influence.

Professor Huang currently serves as Chairman of the Executive Committee of the Applied Mechanics Division of American Society of Mechanical Engineers (ASME), Editor-in-Chief of Journal of Applied Mechanics (ASME Transactions), Co-Editor-in-Chief of Theoretical and Applied Mechanics Letters, and Associate Editor of NPG Flexible Electronics. He has published more than 500 journal papers, including 10 in Science, 5 in Nature and 1 in Cell.



School of Aeronautic Science and Engineering